Structural Insights into Competitive Antagonism in NMDA Receptors

Published: 22 January 2014
on channel: Cell Press
3,337
21

Overactive N-methyl-D-aspartate (NMDA) receptors are implicated in several neurological disorders. However, mechanistic understanding of antagonism in NMDA receptors is limited due to a lack of antagonist-bound structures. Here, structures of antagonist-bound ligand-binding domains of NMDA receptors are presented. For more information, see Jespersen et al., Neuron 81(2).


Watch video Structural Insights into Competitive Antagonism in NMDA Receptors online without registration, duration hours minute second in high quality. This video was added by user Cell Press 22 January 2014, don't forget to share it with your friends and acquaintances, it has been viewed on our site 3,337 once and liked it 21 people.