Oxygen Content And Oxygen Delivery - Concepts and Equations Explained Clearly
Oxygen content and oxygen delivery are two concepts that are critical to understand how the body functions and what happens when that function breaks down. In this video we explain these processes in a clear and full manner with clinical examples included.
Aerobic metabolism goes through the Kreb's Cycle and ends in Oxidative Phosphorylation, which creates the bulk of the body's energy in the form of ATP. Oxygen is critical to this pathway and without it cells are forced to primarily utilize anaerobic metabolism creating lactate and very few ATP. This is why oxygen content and oxygen delivery are so critical to understand.
Oxygen content is the amount of oxygen contained in the arteries. There are two general components of this being the oxygen attached to the hemoglobin molecules in the red blood cells and the amount of oxygen dissolved in the arteries. As such, the equation for oxygen content includes hemoglobin, oxygen saturation of the hemoglobin, and the partial pressure of arterial oxygen using two constants to convert the units to milliliters of oxygen per deciliter of blood. We dive into this equation and explain it in a way that makes sense, including examples using normal numbers, anemia, hypoxemia, and hyperoxia.
Oxygen delivery is the amount of oxygen delivered through the blood stream to the tissues. This is based on the cardiac output and the oxygen content with cardiac output being a result of stroke volume and heart rate. We again decipher this equation in a way that makes sense using the concepts behind it. We provide examples of the calculation.
Lastly, we go through different parts of oxygen content and delivery that can go awry clinically and how to best intervene.
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DISCLAIMER THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.
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