preformulation studies (complete) || Unit 1 || industrial pharmacy 5th semester || Carewell Pharma
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industrial pharmacy 5th semester unit 1
preformulation studies in industrial pharmacy
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Syllabus :-
UNIT 1
Preformulation Studies: Introduction to preformulation, goals and objectives, study of
physicochemical characteristics of drug substances.
a. Physical properties: Physical form (crystal & amorphous), particle size, shape, flow
properties, solubility profile (pKa, pH, partition coefficient), polymorphism
b. Chemical Properties: Hydrolysis, oxidation, reduction, racemization, polymerization
BCS classification of drugs & its significant
Application of preformulation considerations in the development of solid, liquid oral and
parenteral dosage forms and its impact on stability of dosage forms.
Queries -
bcs classification of drugs
physical properties of preformulation studies
chemical properties of preformulation studies
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Chapters :-
00:00 Industrial pharmacy
02:59 Intro + Goal + Objectives
16:49 Physical properties
35:30 Flow properties
53:01 Solubility profile
1:09:48 Polymorphism
1:14:44 Chemical properties
1:25:00 BCS - Biopharmaceutical Classification System
1:37:44 Stability Analysis
1:43:04 Preformulation consideration
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