#22916
Platelet Rich Plasma peri-urethral Injections for the treatment of Stress Urinary Incontinence.
Clavijo J1, Boggia B2, Castillo E1, Gutierrez F1, Maglia L1, Badia H1
1. CASMU Hospital, 2. Hospital Pereira-Rossell
KEYWORDS: Stress Urinary Incontinence, Surgery, Grafts: Biological, New Instrumentation, Quality of Life (QoL)
Stress urinary incontinence (SUI) is a serious problem that affects 20% of adult women. According to the integral theory of continence, injury to the pubourethral and urethropelvic ligaments are the main causes of SUI. Current surgical techniques attempt to restore the urethra to the position prior to ligament damage, increase its resistance and improve its support. Periurethral injections increase urethral resistance. Platelet Rich Plasma with Fibrin (PRPF) is an injectable autologous substance with adhesive, haemostatic, and bulking characteristics. It has been shown to be useful in the repair of ligaments and musculoskeletal injuries[1]. PRPF has been used to repair vesico-vaginal fistulas and for the treatment of penile conditions[2].
Periurethral injections have been performed with autologous, heterologous and synthetic substances. PRPF is autologous, has very few known complications, and is relatively inexpensive. The theoretical concept of the use of PRPF for the treatment of SUI has already been described. An animal experiment confirmed the increase in urine leakage pressure after the application of periurethral PRPF[3] .
Periurethral injection of PRPF in females was described by Matz [2]. We describe our current technique and clinical pathway in female patients with SUI.
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