Costa Bachas, PhD, Amsterdam University Medical Center, Amsterdam, Netherlands, comments on the challenges of implementing computational measurable residual disease (MRD) assessment in clinical practice. He highlights the need for thorough validations of algorithms to comply with regulatory requirements and medical equipment regulations. Dr Bachas emphasizes the importance of explainable statistical modeling to ensure reliable and interpretable results, particularly in stratifying therapy decisions for patients. This interview took place at the 19th International Symposium on Acute Leukemias (ISAL XIX) in Munich, Germany.
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