How Proteins Tilt and ‘Breathe’ on Flu Viruses | Headline Science
The potential “tripledemic” of influenza, SARS-CoV-2 and RSV (respiratory syncytial virus) infection continues to be a concern. Vaccines remain the best defense against COVID-19 and influenza, with the flu vaccine mainly targeting two proteins on the virus’s surface. Now, researchers in ACS Central Science report that simulations show the proteins can tilt and wave in “breath-like” motions, which could be exploited to better defend against the flu.
“Breathing and Tilting: Mesoscale Simulations Illuminate Influenza Glycoprotein Vulnerabilities” - Rommie E. Amaro, Ph.D. (corresponding author)
https://pubs.acs.org/doi/10.1021/acsc...
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