BrainMap: Imaging the Anatomical and Functional Brain Micro-Organization
Nikolaus Weiskopf, PhD, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Imaging the Anatomical and Functional Brain Micro-Organization
BrainMap, July 14th, 2023
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Athinoula A. Martinos Center for Biomedical Imaging
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0:00 Introduction (Due to technical issues, the slides are shown in the beginning)
3:43 Importance of brain micro-organization (Due to technical issues, there is echoing until ~ 16:10)
4:52 Micro-organization imaging and in-vivo histology using (hMRI)
6:39 Modelling strategy: multi-contrast, multi-Level
8:16 Three-pronged interdisciplinary approach
8:58 Overview
9:29 Multi-parameter mapping (MPM) using multi-echo FLASH
10:24 Multi-parameter maps (MPM) at 7T using optical prospective motion correction (PMC)
11:22 R1 myelin maps compared to fMRI retinotopy
13:00 Inter-areal feature: myelination of thin, thick and pale stripes in secondary visual cortex (V2)
14:09 Intra-areal features: stripes in secondary visual cortex (V2)
17:34 Complex Myelin: Histology compared to quantitative MRI
19:00 MALDI-Mass Spectrometry Imaging of lipid components
22:44 Imaging Superficial White Matter (SWM)
25:25 Quantitative Iron Maps Correlate with MR Contrast
27:26 Mapping oligodendrocytes and myelinated fibers
29:39 Mapping short association fibers (SAF) with 300mT/m Connectom MRI: visual system
30:29 Mapping short association fibers (SAF): visual system
33:36 Mapping SAF: predicting retinotopic organization
35:26 SAF contribution to connective field sizes
39:40 Evolution of hominoid brain connectomics (EBC)
45:59 Quantitative 3D iron maps with microscopic resolution
50:57 N1 and the swallow tail overlay only partly N1 is thinner and extends beyond the swallow tail sign.
52:30 Discussion
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