Chloroform sunghne Ke Kitne der baad me Insan behosh hota hai?
Moldenhawer, a German pharmacist from Frankfurt an der Oder, appears to have produced chloroform in 1830 by mixing chlorinated lime with ethanol; however, he mistook it for Chloräther (chloric ether, 1,2-dichloroethane).
Samuel Guthrie, an American physician from Sackets Harbor, New York, also appears to have produced chloroform in 1831 by reacting chlorinated lime with ethanol, as well as noting its anaesthetic properties; however, he also believed that he had prepared chloric ether.[17][18][19]
Justus von Liebig carried out the alkaline cleavage of chloral.[20][21]
Eugène Soubeiran obtained the compound by the action of chlorine bleach on both ethanol and acetone.[22]
In 1834, French chemist Jean-Baptiste Dumas determined chloroform's empirical formula and named it.[23] In 1835, Dumas prepared the substance by the alkaline cleavage of trichloroacetic acid. Regnault prepared chloroform by chlorination of chloromethane.[citation needed]
In 1842, Robert Mortimer Glover in London discovered the anaesthetic qualities of chloroform on laboratory animals.[24]
In 1847, Scottish obstetrician James Y. Simpson was the first to demonstrate the anaesthetic properties of chloroform on humans, provided by local pharmacist William Flockhart of Duncan, Flockhart and company,[25] and helped to popularise the drug for use in medicine.[26] By the 1850s, chloroform was being produced on a commercial basis, in Britain about 750,000 doses a week by 1895,[27] by using the Liebig procedure, which retained its importance until the 1960s. Today, chloroform – along with dichloromethane – is prepared exclusively and on a massive scale by the chlorination of methane and chloromethane.[8
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