Ricin | Wikipedia audio article
This is an audio version of the Wikipedia Article:
https://en.wikipedia.org/wiki/Ricin
00:00:42 1 Biochemistry
00:01:50 1.1 Biosynthesis
00:03:09 1.2 Structure
00:04:53 1.3 Entry into the cytoplasm
00:07:58 1.4 Ribosome inactivation
00:09:16 1.5 Depurination reaction
00:10:56 2 Toxicity
00:16:29 2.1 Overdose
00:17:24 3 Therapeutic applications
00:18:56 4 Regulation
00:19:44 5 Chemical or biological warfare agent
00:23:20 6 Developments
00:24:10 7 Incidents
00:27:15 8 In popular culture
00:28:26 9 See also
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SUMMARY
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Ricin ( RY-sin), a lectin (a carbohydrate-binding protein) produced in the seeds of the castor oil plant, Ricinus communis, is a highly potent toxin. A dose of purified ricin powder the size of a few grains of table salt can kill an adult human. The median lethal dose (LD50) of ricin is around 22 micrograms per kilogram of body weight if the exposure is from injection or inhalation (2 milligrams for an average adult). Oral exposure to ricin is far less toxic as some of the poison is inactivated in the stomach. An estimated lethal oral dose in humans is approximately 1 milligram per kilogram.
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