Merritt Burch - A meta GWAS reanalysis of twenty years of quantitative traits in maize
The magnitude and prevalence of pleiotropy in maize have been shown to have widespread effects ranging from flowering time, leaf architecture, and inflorescence traits. However, the impact that pleiotropy has genome-wide on maize phenotypes is largely unknown. This project investigates the extent to which pleiotropy impacts phenotypes within maize and attempts to understand their potential causality through the lens of gene expression, chromatin status, sequence conservation, and tissue-specific expression. Knowledge of how the pleiotropic nature of loci impacts traits has applications in plant breeding programs to improve trait prediction models
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