American College Of Physicians Officially Recommends GLP-1s Like Ozempic
The American College of Physicians issued new guidelines for Type 2 diabetes treatment, which for the first time recommends the use of GLP-1s and another class of diabetes drugs called SGLT-2s alongside metformin, though this may exacerbate the ongoing drug shortages of several GLP-1s. Some GLP-1 medications are already in a shortage due to high demand. Though all doses of diabetes drug Ozempic are available, all doses of Nordisk’s weight loss drug Wegovy are in a shortage except for its highest dose, 2.4 milligrams. Nordisk hasn’t provided a timeframe for when the supply will improve. Nordisk told Forbes it will gradually increase supply of all doses of Wegovy throughout the rest of the year, and it said in its annual report it was thinking of ways to remove “bottlenecks” from the supply chain like by making disposable injection pens. All doses of Eli Lilly’s diabetes drug Mounjaro and its weight loss drug Zepbound—both contain the active ingredient tirzepatide—are in a shortage until at least the end of June, except for the 2.5 milligram doses, according to the Food and Drug Administration’s drug shortage database. The 2.5 milligram doses are the lowest dosage Lilly offers, and often the dose patients start on when they’re first prescribed the drugs. Patients typically stay on a dose for at least four weeks and then progress to the next-highest dose, but this may not be an option for some if the drugs are still in short supply. Lilly told NBC News it plans on opening a new manufacturing facility in North Carolina by the end of the year to help increase supply.38.4 million. That’s how many Americans had diabetes in 2021, totaling 11.6% of the population, according to data from the American Diabetes Association. Another 97.6 million over the age of 18 had prediabetes. Much research on the effects of GLP-1s on diabetes and weight loss has been conducted. During a 72-week trial, participants saw a “substantial and sustained reduction in body weight” by taking tirzepatide, regardless of the drug dosage, a 2022 study found. Participants taking semaglutide—the active ingredient in Ozempic and Wegovy—lost an average of 15% of their body fat, according to a 2021 study. German researchers found semaglutide offered improvements in blood sugar and weight loss for Type 2 diabetics after a six-month trial. Tirzepatide “robustly” improved blood glucose levels and aided in weight loss in patients with Type 2 diabetes, according to research published in JAMA Network Open.
All data is taken from the source: http://forbes.com
Article Link: https://www.forbes.com/sites/ariannaj...
#newspak #bbcnewsworld #newstodayinusa #newsworldfox #newsworldabc #usanewstoday #
Watch video American College Of Physicians Officially Recommends GLP-1s Like Ozempic online without registration, duration hours minute second in high quality. This video was added by user Business News 20 April 2024, don't forget to share it with your friends and acquaintances, it has been viewed on our site 10 once and liked it 0 people.