A study of dizygotic twins with JAK2-positive MPNs

Published: 15 November 2022
on channel: VJHemOnc – Video Journal of Hematology & HemOnc
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Josef Prchal, MD, University of Utah, Huntsman Cancer Institute, Salt Lake City, UT, describes an unusual twin study in which two twins developed myeloproliferative neoplasms (MPNs) at different times. The study showed that it is possible to develop MPNs up to 30 years after the occurrence of a JAK2 mutation and suggested that JAK2 mutations can be passed from one twin to other possibly through a shared placenta. This interview took place at the 14th International Congress on Myeloproliferative Neoplasms (MPN Congress) held in New York City, NY.

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