The History of Phage Therapy

Published: 04 February 2024
on channel: Patrick Kelly
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Phage therapy uses viruses called bacteriophages to destroy specific bacteria. Scientists are hopeful that they could become a tool to fight antibiotic-resistant germs. In this video, Patrick Kelly guides you through the history of phage therapy's development.

☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️

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📜 S O U R C E S 📜
The Good Virus by Tom Ireland https://www.amazon.com/Good-Virus-Ama...
The Perfect Predator by Stephanie Strathdee https://www.amazon.com/Perfect-Predat...
Annotated script here:   / phage-video-is-97650618  
Bacteriophage Therapy of Bacterial Infections: The Rediscovered Frontier (2021)
https://www.mdpi.com/1424-8247/14/1/34
Standardized bacteriophage purification for personalized phage therapy (2020) https://www.nature.com/articles/s4159...
Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria (2019) https://www.cell.com/cell-host-microb...
Phage Cocktail Development for Bacteriophage Therapy (2021) https://www.ncbi.nlm.nih.gov/pmc/arti...
Hankin paper (1896) https://archive.org/details/annalesde... https://www.tandfonline.com/doi/pdf/1...
A Brief History of Shigella (2018) https://www.ncbi.nlm.nih.gov/pmc/arti...
An Early History of Phage Therapy in the United States (2021) https://www.ncbi.nlm.nih.gov/pmc/arti...
Bacteriophage prehistory (2011) https://www.ncbi.nlm.nih.gov/pmc/arti...
The virus in the rivers: histories and antibiotic afterlives of the bacteriophage at the sangam in Allahabad (2020) https://royalsocietypublishing.org/do...
Bacteriophage Therapy (2001) https://www.ncbi.nlm.nih.gov/pmc/arti...
The Third Age of Phage (2005) https://journals.plos.org/plosbiology...
An invisible microbe that is antagonistic to the dysentery bacillus (1917) by F. d’Herelle — translation of original French https://www.sciencedirect.com/science...
Le bacteriophage (1921) by D’Herelle https://archive.org/details/lebactrio...
Bacteriophage and Staph skin infections (1921) https://gallica.bnf.fr/ark:/12148/bpt...
Cholera and Plague in India: The Bacteriophage Inquiry of 1927-1936 https://web.archive.org/web/201708111...
The Adoption and Survival of Bacteriophage Therapy in the USSR (2018) https://academic.oup.com/jhmas/articl...
The prospect for bacteriophage therapy in Western medicine (2003) https://www.nature.com/articles/nrd11...
An interview with Elizabeth Kutter https://www.ncbi.nlm.nih.gov/pmc/arti...

IMAGES
Portrait of Steffanie A. Strathdee by Scott Lafee for Triton Magazine. CC-BY-SA 4.0 https://en.wikipedia.org/wiki/Steffan...
https://creativecommons.org/licenses/...
Intralytix Headquarters by Rayford Payne. CC-BY-SA 4.0
https://upload.wikimedia.org/wikipedi...
   • Cholera bacteria can survive antibiot...  


💻 C O N T A C T 💻
patkellyteaches [at] gmail.com

⌛T I M E S T A M P S ⌛
0:00 intro
0:48 What is a Phage
2:00 Ernest Hankin
5:18 Fredrick Twort
6:50 Felix d’Herelle
16:52 Phage Therapy in the Soviet Union
22:19 Phage Therapy in the USA
25:16 Challenges to phage therapy
28:09 Why are people hopeful?

#historyofmedicine #medicalhistory


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