Salk Institute Develops Safe Diet Pill Fexaramine

Published: 05 January 2015
on channel: Quantum Day
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Article Here: http://www.quantumday.com/2015/01/sci...

A new fat burning compound can lead to weight loss without causing side effects. The pill, fexaramine, remains in the intestine rather than dissolve in the blood stream like other appetite suppressants or caffeine-based diet drugs.

Researchers at the Salk Institute have developed a fat-burning compound called fexaramine that leads to weight loss without typical side effects in animal models. Fexaramine tricks the body into reacting as if it has consumed calories and could lead to an effective treatment for type 2 diabetes and obesity in humans.

Fexaramine works by making the body think that it has consumed calories which causes it to burn fat. In trials, researchers who developed the drug at the Salk Institute found that they effectively stopped weight gain, lowered cholesterol, controlled blood sugar and minimized inflammation.

Initially they used fexaramine in obese and diabetic mice, the researchers note that in five weeks of daily intake, the mice stopped gaining weight, lost fat and had lower blood sugar and cholesterol levels than untreated mice. In addition, the mice had a rise in body temperature--which signals metabolism ramping up--and some deposits of white fat in their bodies converted into a healthier, energy-burning beige form of the tissue.

The effects of the drug in mice led the scientists to believe that fexaramine can be an effective treatment for type 2 diabetes and obesity in humans.

Credit: Salk Institute (http://www.salk.edu/)


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