Key CF3 Chemistry (Important Papers)

Published: 02 July 2024
on channel: That Chemist
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Important Papers covers various chemical reactions, mechanisms, and research papers in the field of organic chemistry, providing examples and explanations for each research paper.

In this video, I discuss major articles from fluorine chemistry which are widely overlooked by the majority of synthetic chemists - these are the bread and butter of fluorine chemistry.

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References:
Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond - https://doi.org/10.1021/cr400473a
Togni Reagents – Electrophilic CF3 - https://doi.org/10.1021/cr500223h
Advances in the Development of Trifluoromethoxylation Reagents - https://pubs.acs.org/doi/10.3390/sym1...
Efficient Difluoromethylation of Alcohols Using TMSCF2Br - https://onlinelibrary.wiley.com/doi/a...

Org syn prep of togni reagent: https://doi.org/10.15227/orgsyn.088.0168
TMSCF2Br synthesis: https://doi.org/10.1016/j.jfluchem.20...
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