Controlling crystals for more reliable drugs | Headline Science

Published: 22 July 2024
on channel: American Chemical Society
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Sometimes, compounds crystallize in unexpected ways. This is a problem for drug manufacturers, who need to create consistent products. Scientists are working to understand why substances take on different crystal forms, called polymorphs, under different conditions. Recently, they’ve shown that impurities can affect the relative stability of those forms.

Read the paper: https://doi.org/10.1021/acs.cgd.4c00503
(Corresponding author: Fredrik L. Nordstrom, Ph.D.)

Video credits:
Written by Anne Hylden
Produced by Anne Hylden, Kerri Jansen and Andrew Sobey
Edited by Vangie Koonce
Narrated by Anne Hylden
Executive produced by Matthew Radcliff

Research videos from Mitchell Paolello and Seyed Sepehr Mohajerani

Scientific consultant: Gerard Capellades, Ph.D.

Additional video: Darren Weaver

Hand models: Anne Hylden, Kerri Jansen and Allison Tau

Music: “Handwriting” by Frank Jonsson from Epidemic Sound

Sound effects from Soundsnap

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