Carmen Villalobos as María Dolores "Lola" Volcán
Jencarlos Canela as Andrés Suárez / Andrés Santacruz
Angélica María as Isabel "Chabela" Volcán
Ana Layevska as Débora Noriega, main female villain, hates Lola, obsessed with Andres, mistress of Marcelo, murdered him, killed by Diana
Fabián Ríos as Ángel Meléndez, main male villain, in love with Lola, killed Tiberio, Fulgencio and Diana, shot by Andres to save Lola
Secondary
Katie Barberi as Victoria "Vicky" de Noriega, villain, later turns good
Carlos Torres as Rodrigo Suárez, police officer, father of Andres, in love with Soledad
Rossana San Juan as Soledad Volcán, former lover of Tiberio, mother of Lola, in love with Rodrigo. She is kidnapped by Débora, and is held captived by Tiberio, and then Angel for over a year (at one point is presumed dead) and it becomes a main focus of the series to find her.
Gerardo Murguía as Marcelo Santacruz, villain, hates Andres and Lola, kills Veronica, murdered by Débora
Alejandro Suárez as Diógenes Rugeles, in love with Lola, hates Andres
Liannet Borrego as Verónica Alcázar, in love with Daniel, hates Adela, and killed by Marcelo
Mauricio Hénao as Daniel Santacruz, villain, later good, in love with Adela but left her for Veronica, becomes a drug addict, ends up together with Adela
Carlos Ferro as Camilo Andrade, a lawyer, Andres' best friend, is in love with Sofia
Cynthia Olavarría as Sofía Palacios, a psychiatrist, Andres' aunt, in love with Camilo
Roberto Huicochea as José "Pepe" Linares, Adela's grandfather, in love and marries to Etelvina
Rubén Morales as Ramón Noriega, villain, accomplice of Marcelo, the father of Débora, husband of Vicky, is murdered by Angel
Paloma Márquez as Adela "Adelita" Linares, Lola's best friend, turns against her family and becomes a prostitute but escapes a reunites with her family, she's initially in love with Daniel, then Fulgencio Lopez (whom would be the father of her child), but ends up together with Daniel after Lopez is murdered.
Lino Martone as Fulgencio López, in love with Adela (is the father of her child), killed by Angel
Jeannette Lehr as María Etelvina Rengifo / Eduviges Rengifo, villain, later good, is in love with Diógenes, then falls in love and marries Pepe
Carolina Tejera as Diana Mirabal, villain, in love with Andres, has a baby from Angel, killed by him
Roberto Mateos as Tiberio Guzman, villain, mafioso, real father of Lola, rapes Soledad, killed by Angel
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