Urinary Tract Infection, Causes, Signs and Symptoms, Diagnosis and Treatment.
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Chapters
0:00 Introduction
1:03 Causes of urinary tract infection
1:56 Signs and Symptoms of urinary tract infection
2:36 Diagnosis of urinary tract infection
3:29 Treatment of urinary tract infection
A urinary tract infection (UTI) is an infection that affects part of the urinary tract.[1] When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidney infection (pyelonephritis).[10] Symptoms from a lower urinary tract infection include pain with urination, frequent urination, and feeling the need to urinate despite having an empty bladder.[1] Symptoms of a kidney infection include fever and flank pain usually in addition to the symptoms of a lower UTI.[10] Rarely the urine may appear bloody.[7] In the very old and the very young, symptoms may be vague or non-specific.[1][11]
The most common cause of infection is Escherichia coli, though other bacteria or fungi may sometimes be the cause.[2] Risk factors include female anatomy, sexual intercourse, diabetes, obesity, and family history.[2] Although sexual intercourse is a risk factor, UTIs are not classified as sexually transmitted infections (STIs).[12] Kidney infection, if it occurs, usually follows a bladder infection but may also result from a blood-borne infection.[13] Diagnosis in young healthy women can be based on symptoms alone.[4] In those with vague symptoms, diagnosis can be difficult because bacteria may be present without there being an infection.[14] In complicated cases or if treatment fails, a urine culture may be useful.[3]
In uncomplicated cases, UTIs are treated with a short course of antibiotics such as nitrofurantoin or trimethoprim/sulfamethoxazole.[7] Resistance to many of the antibiotics used to treat this condition is increasing.[1] In complicated cases, a longer course or intravenous antibiotics may be needed.[7] If symptoms do not improve in two or three days, further diagnostic testing may be needed.[3] Phenazopyridine may help with symptoms.[1] In those who have bacteria or white blood cells in their urine but have no symptoms, antibiotics are generally not needed,[15] although during pregnancy is an exception.[16] In those with frequent infections, a short course of antibiotics may be taken as soon as symptoms begin or long-term antibiotics may be used as a preventive measure.[17]
About 150 million people develop a urinary tract infection in a given year.[2] They are more common in women than men.[7] In women, they are the most common form of bacterial infection.[18] Up to 10% of women have a urinary tract infection in a given year, and half of women have at least one infection at some point in their lifetime.[4][7] They occur most frequently between the ages of 16 and 35 years.[7] Recurrences are common.[7] Urinary tract infections have been described since ancient times with the first documented description in the Ebers Papyrus dated to c. 1550 BC.[19]
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