von Willebrand disease - Disease of Platelet adhesion and aggregation - MADE EASY
von Willebrand disease is the most common hereditary coagulation disorder. It arises from either qualitative or quantitative deficiency of von Willebrand factor, which is a protein that is required for platelet adhesion. There are 4 different types. Type 1 is the most common type. It is an Autosomal Dominant disorder. It decreases the levels of Von Willerbrand factors, which are proteins that are required for platelet adhesion. This decreased level of Von Willerbrand factors is going to result in problems with platelet adhesion.
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