Dr. Hedy Kindler of the University of Chicago Medicine joins us to discuss precision medicine and targeted therapies for the treatment of mesothelioma. Dr. Kindler explains the mechanisms of action for several molecular pathways associated with tumor growth and/or inhibition. She also discusses three specific therapeutic options available through clinical trials like CPI-0209 and olaparib (PARP inhibitors) targeted at the BAP1 tumor mutation; and the VT3989 targeting the NF2 pathway.
While these treatment options are still in early clinical trial phases, they target specific known tumor mutations, which makes them more precise than traditional chemotherapy treatment.
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